The 'Most Esoteric Bitch' meme emerged as a humorous subversion of the 'not like other girls' trope, focusing specifically on internet subcultures that prize obscurity and intellectual gatekeeping. It typically features a character claiming to be the most 'esoteric'—meaning their interests are understood by only a small number of people with specialized knowledge. The meme gained significant traction on platforms like Twitter and Instagram within 'weird girl' circles, where users poke fun at their own obsessions with astrology, continental philosophy, or avant-garde media. It serves as both a badge of honor for niche hobbyists and a self-aware parody of how performative underground culture can be.