The Sleep-Deprived SpongeBob meme features a screenshot from the SpongeBob SquarePants episode 'Home Sweet Pineapple,' where SpongeBob appears incredibly haggard with bloodshot eyes and disheveled pores. It gained massive popularity across Twitter and Reddit as a universal symbol for burnout, insomnia, or the physical state of being 'up too late.' Users typically pair the image with captions about finishing assignments at the last minute, binge-watching shows, or regretting poor life choices at 3 AM. Its visceral depiction of fatigue makes it one of the most relatable SpongeBob templates in the meme canon.