The 'Mr. Krabs Give It Up For Day' meme comes from the SpongeBob SquarePants episode 'Fear of a Krabby Patty.' In the scene, the Krusty Krab has been open for 24 hours a day, leading to a manic, sleep-deprived Mr. Krabs ringing a bell and shouting 'Give it up for day 15!' to an exhausted Squidward. The internet adopted this image to represent burnout, the feeling of being stuck in a repetitive cycle, or to countdown days during long-awaited events. It remains a staple for expressing the physical and mental toll of long-term endurance.