The 'Did You Try the Medicine Drug?' meme originates from a webcomic parody of the medical drama House M.D., illustrating the show's repetitive diagnostic formula in an absurd, stripped-back style. The comic features a stylized Dr. House suggesting a 'medicine drug' to a patient who dismisses the idea as something only 'stupid people' do, prompting House's iconic realization: 'I am also an idiot.' Since its rise on Tumblr and Reddit, the meme has been widely used to mock obvious solutions, professional incompetence, or moments of shared stupidity. It perfectly captures the 'anti-intellectual' humor popular in niche internet circles where expert advice is boiled down to its most nonsensical form.