The 'Ana de Armas Saying Smile' meme originates from the 2017 sci-fi film Blade Runner 2049, featuring the holographic AI Joi (Ana de Armas) and the protagonist K (Ryan Gosling). In this emotionally charged scene, Joi tells a physically and mentally exhausted K to 'smile,' highlighting the artificial yet deep connection between them. Online, the template became a viral sensation used to depict the sharp contrast between someone trying to offer comfort or toxic positivity and another person who is clearly struggling or 'dead inside.' It perfectly captures the vibe of forcing a happy face during stressful situations or highlighting the irony of synthetic happiness in a bleak world.