The '21, Can You Do Somethin' For Me?' meme originated from the 2022 track 'Rich Flex' by Drake and 21 Savage, specifically the intro where Drake adopts an unusually melodic, almost pleading tone. Social media users, particularly on TikTok and Twitter, quickly began parodying the delivery, characterizing Drake as 'zesty' or overly dramatic. The phrase 'Do your thing, 21' became a versatile punchline used to encourage someone to show off or complete a specific task in a humorous way. Today, the meme is a staple of hip-hop internet culture, used to satirize Drake's persona or to hilariously request favors from friends using the singer's signature inflection.