The 'Yass Pills' meme is a staple of modern internet culture, stemming from the broader 'Yassification' trend that took social media by storm in late 2021. The meme typically depicts a blister pack of medication edited to feature 'Yass' branding, symbolizing a metaphorical dose of confidence, glamour, or fabulousness. It is often used to describe a sudden transformation or 'glow-up'—where a person or fictional character becomes hyper-stylized or overtly fashionable. Rooted in LGBTQ+ ballroom culture slang, the meme has evolved into a versatile tool for Gen Z and Millennials to celebrate self-expression, irony, and the humorous pursuit of aesthetic perfection.