The 'Pills That Make You Stare' meme is derived from a webcomic format where a character consumes medication that forces them to gaze intensely at a specific subject. The humor lies in the labels placed on the bottle, which dictate exactly what the character will be fixated on in the final panels. Since its rise in popularity on social media platforms like Reddit and Twitter, the template has become a go-to for highlighting uncomfortable truths, personal obsessions, or relatable bad habits. It effectively uses a four-panel progression—from reading the bottle to the inevitable, blank-eyed stare—to deliver a punchline that resonates with anyone who has ever felt 'called out' by a meme.