Super Bowl 50 memes primarily stem from the 2016 championship game between the Denver Broncos and the Carolina Panthers. The most popular variations feature Von Miller's dominant performance against Cam Newton, specifically the iconic strip-sack that defined the game's defensive struggle. Following the game, images of a dejected Cam Newton in a hoodie during his post-game press conference also became a viral sensation, representing peak 'sore loser' energy or total emotional exhaustion. The meme is frequently used to illustrate scenarios where a high-energy or confident individual is suddenly humbled by a superior force or an unexpected reality check.