The Peter Griffin running away meme stems from various episodes of the long-running animated series Family Guy, most notably during his frequent battles with Ernie the Giant Chicken. The image captures the show’s signature slapstick humor, showing Peter in a state of frantic, wide-eyed terror as he sprints from danger. Online, the template became a viral sensation as a way to represent people avoiding responsibilities, awkward social encounters, or impending doom. Its versatility across social media platforms like TikTok and Twitter has solidified its place as a go-to reaction image for high-stress, comedic scenarios.