The 'Miles Morales Running From Miguel O'Hara' meme originates from the 2023 blockbuster Spider-Man: Across the Spider-Verse, specifically during the high-octane sequence where Miles attempts to escape the Spider-Society headquarters. The template captures the terrifyingly determined Miguel O'Hara (Spider-Man 2099) lunging through the air while a panicked Miles frantically maneuvers to stay ahead. Since the film's release, the image has become the internet’s favorite way to depict someone desperately avoiding their responsibilities, inevitable consequences, or an overbearing authority figure. Its popularity stems from the high-stakes kinetic energy and the dramatic contrast between the hunter and the hunted, making it a perfect visual metaphor for any relatable 'run for your life' scenario.