The 'Mario and Luigi vs. Sephiroth' meme highlights the hilarious power disparity and unexpected competence of the Mario brothers when facing the intimidating Final Fantasy VII antagonist. It primarily draws inspiration from the Mario & Luigi RPG series, where the duo's ability to dodge and counter-attack any move—no matter how god-like—makes them technically invincible in the eyes of fans. The meme gained significant traction following Sephiroth's reveal in Super Smash Bros. Ultimate, often used to mock edgy villains by suggesting they would be easily defeated by the plumbers' simple, rhythmic combat mechanics and 'Bros. Attacks'.