The 'Infinity War Is The Most Ambitious Crossover Event In History' meme originated from a promotional tweet by Marvel Studios in March 2018, just before the release of Avengers: Infinity War. Twitter users quickly turned the bold claim into a humorous template by pairing the quote with screenshots of unexpected or bizarre collaborations from television, film, and real life that predated the MCU. From Disney Channel sitcom specials like 'That's So Suite Life of Hannah Montana' to weird commercial cameos, the meme serves as a nostalgic way to mock hype culture while celebrating the chaotic crossovers of the past. It remains a staple for pointing out the most unlikely pairings in pop culture history.