Ghetto Smosh refers to a series of surreal, low-budget 3D animated parodies of classic Smosh sketches, primarily popularized by the creator Real Talk 45. Featuring distorted, bootleg versions of Ian Hecox and Anthony Padilla, the series reimagines early 2000s YouTube nostalgia through an absurdist lens with high-energy voice acting and street-style dialogue. The meme gained massive traction on TikTok and Twitter as a form of 'ironic' humor, where the janky animation style and aggressive delivery are used to subvert expectations. It represents a niche intersection of internet subcultures, blending early YouTube history with modern 'shitposting' aesthetics.