The COVID-19 Omicron Variant meme emerged in late 2021 following the discovery of the highly transmissible B.1.1.529 strain. Internet users quickly turned to humor to cope with the sudden shift in global pandemic progress, often portraying the variant as a persistent 'final boss' or a sudden interruption to holiday plans. Common templates include comparisons between the Delta and Omicron variants, or personifying the virus as it bypasses previous vaccine defenses. These memes capture the collective fatigue and absurdity of navigating the ongoing waves of the pandemic through a lens of dark humor and shared frustration.