The 'You Know How Much I Sacrificed' meme features Willem Dafoe as Norman Osborn in the 2002 film Spider-Man. The scene occurs when the board of directors at Oscorp informs Norman that they are selling the company and firing him. Overwhelmed by betrayal, Norman shouts the iconic line, highlighting his desperation and the years he dedicated to his research. It gained internet fame as a reaction image used to satirize situations where someone puts in a disproportionate amount of effort for a small reward, or when their hard work goes unappreciated. The meme captures a perfect blend of genuine pathos and over-the-top campiness that Willem Dafoe is celebrated for.