The Subway restaurant meme, specifically the 'My Brother in Christ' variant, originated from a viral tweet in 2022 that repurposed an older meme about people complaining that 'Subway sucks.' The punchline points out the inherent irony: because Subway is an assembly-line style restaurant where customers choose every ingredient, any 'bad' sandwich is ultimately the customer's own fault. The phrase 'My Brother in Christ' was used to replace a more profane term from the original 2014 version, giving the meme a mock-pious and hilarious tone. It has since evolved into a universal template for highlighting self-inflicted problems and the importance of personal accountability in a humorous way.