The phrase 'Your Brain on Drugs' originally comes from an anti-drug campaign in the 1980s, which featured vivid imagery to showcase the negative effects of drug use. This particular meme references a humorous remix of that concept, combining elements of absurdity with a catchy phrase that draws attention. In this video meme, the juxtaposition of everyday kitchen activities with drug-related imagery creates an ironic and comedic effect, making it relatable for viewers who enjoy dark humor.