Sneakers O'Toole is a minor yet iconic character from the Family Guy episode 'Whistle While Your Wife Works.' He is known for his unwavering refusal to remove his sneakers, even in the most inappropriate situations, famously shouting 'I'm not takin' 'em off!' before sprinting away. The meme gained popularity as a relatable way to express stubbornness, a refusal to follow social norms, or an obsession with a particular item of clothing. It is frequently used in the sneakerhead community and by anyone who finds themselves in a situation where they are unwilling to compromise on their personal comfort or choices.