The Smithers vs Strippers meme originates from the classic Season 1 episode of The Simpsons titled 'Homer's Night Out,' which first aired in 1990. In this scene, Waylon Smithers is shown covering his eyes in distress while surrounded by exotic dancers at a bachelor party. The image gained viral status as a relatable reaction for anyone trying to maintain their integrity, avoid spoilers, or stay focused on a goal while being surrounded by temptations. It has since become a staple in internet culture for expressing feelings of being 'too pure' or simply uncomfortable in certain social situations.