The Serotonin meme typically utilizes the chemical structure of the neurotransmitter responsible for mood stabilization and happiness. It gained massive popularity in wellness, mental health, and science-heavy online communities as a relatable way to discuss emotional well-being. Users often personify the molecule or use it as a label for things that bring them joy, such as pets, food, or hobbies. In many variations, it highlights the desperate search for 'the happy chemical' in everyday life, turning a complex biological process into a humorous commentary on modern stress and the simple things that provide a quick boost of dopamine or serotonin.