The 'Real RX' meme, primarily associated with the song '12 Stout Street' by rapper RX Papi, gained massive traction on TikTok and Twitter for its raw, unfiltered vulnerability. The song's opening line, 'Real RX,' followed by a harrowing account of childhood struggles, became a shorthand for moments of intense honesty or 'trauma dumping' in a relatable context. Often paired with a slowed-down version of the track, the meme is used to contrast a seemingly normal situation with a sudden shift into deep, personal reflection. It captures a specific internet aesthetic of 'realness,' serving as a soundtrack for content where users share surprising or depressing facts about their lives or surroundings.