This meme is a direct reference to the iconic 2004 teen comedy film Mean Girls. In the scene, teacher Ms. Norbury asks the junior girls in the gymnasium to raise their hands if they have ever been personally victimized by the queen bee, Regina George. Since its release, the phrase has become a cultural staple, used across social media to jokingly call out everything from minor inconveniences to frustrating software updates. It perfectly captures the feeling of shared struggle through the lens of early 2000s nostalgia.