The 'Get in, loser' meme originates from the 2004 cult classic teen comedy Mean Girls. In the iconic scene, the 'queen bee' Regina George pulls up in a silver convertible and delivers the line 'Get in, loser, we're going shopping' to the protagonist, Cady Heron. While the original line was about a mall trip, the internet quickly adapted the phrase to include any activity imaginable. It gained significant traction on platforms like Tumblr and Twitter, becoming a universal template for inviting others to join a specific subculture, hobby, or even a self-deprecating situation. It remains a staple of pop culture memes, symbolizing both exclusivity and a humorous call to action.