The PragerU 'The Lockdown Is The Greatest Mistake' meme originated from a tweet posted by the conservative media organization PragerU in April 2020. The tweet's hyperbolic claim—that COVID-19 lockdowns were the single worst event in human history—immediately sparked a wave of mockery and 'ratio' replies across social media. Internet users began pairing the screenshot of the tweet with images of significantly more catastrophic events, such as the Black Death, the asteroid that wiped out the dinosaurs, or various historical wars, to highlight the perceived lack of perspective in the original post. It remains a popular template for pointing out exaggerated political rhetoric or making ironic comparisons between modern inconveniences and genuine global tragedies.