The 'Oh God, He's Going for the Jukebox!' meme stems from a comic panel depicting a man in a state of absolute panic as he witnesses someone approaching a jukebox. It serves as the ultimate visual metaphor for that relatable moment when someone is about to play a controversial, annoying, or overly enthusiastic song that ruins the mood. Since circulating online, the template has evolved to represent any situation where an individual is about to unleash a niche obsession or a 'vibe-killing' opinion upon an unsuspecting crowd. Its frantic energy makes it a favorite for roasting friends' musical tastes or social habits.