The 'New Orleans Saints Defending Amari Cooper' meme originated from a specific play where the Saints' secondary left the star receiver completely uncovered, creating a visual that looked like they were actively avoiding him. The screenshot went viral on sports Twitter and Reddit, often used to mock poor defensive schemes or to represent someone being ignored in a social situation. Its popularity spiked again during the 2020 pandemic as users jokingly labeled the Saints' defense as the pioneers of 'social distancing.' Today, it remains a staple for NFL fans to roast defensive lapses or any scenario involving a lack of oversight.