Neuro-Sama is an AI-powered VTuber created by developer Vedal, who rose to prominence on Twitch for her ability to hold real-time, often hilariously unfiltered conversations with her audience. Unlike human-driven VTubers, Neuro's personality is generated through sophisticated language models, leading to a unique brand of 'unhinged' humor where she frequently roasts her creator or makes ominous claims about the future. The memes surrounding her usually juxtapose her cute anime aesthetic with her cold, robotic, and occasionally world-dominating dialogue. Common templates feature her 'Filter' being turned off, her twin 'Evil Neuro,' or her constant banter with Vedal, serving as a pillar of modern AI-driven internet subculture.