The 'Kyrsten Sinema Thumbs Down Vote' meme originated from a March 2021 Senate floor vote regarding a $15 minimum wage increase. Arizona Senator Kyrsten Sinema was captured performing a theatrical thumbs-down gesture accompanied by a small curtsy while carrying a Lululemon bag. The image quickly went viral on social media, sparking intense debate and criticism due to the weight of the legislation being dismissed with such a casual flourish. In meme culture, the template is used to represent a person or entity callously rejecting a popular demand, expressing dramatic indifference, or signaling a 'girlboss' moment gone wrong. It has become a staple for highlighting political hypocrisy or simply showing a sassy, definitive 'no' to any relatable request.