The 'Jesse, What the Fuck Are You Talking About' meme originates from the critically acclaimed AMC series Breaking Bad, specifically featuring a scene where Walter White reacts with total bewilderment to one of Jesse Pinkman's frantic explanations. While the original scene carries significant dramatic weight within the show's narrative, the internet transformed it into a versatile template for reacting to bizarre, nonsensical, or overly complex internet theories. It typically involves a top panel filled with a long-winded, often absurd 'schizopost' or niche conspiracy, followed by Walter’s aggressive dismissal in the bottom panel. The meme gained massive traction on platforms like Reddit and Twitter as a way to mock fan theories, cryptocurrency jargon, and specific subculture inside jokes that sound like gibberish to outsiders.