The 'And I Oop' meme originated from a YouTube video uploaded by drag queen Jasmine Masters in 2019 titled 'I'm Comin' Out'. While discussing her habits, she accidentally hit her testicles, causing a sudden, high-pitched gasp and the phrase 'And I oop—' before attempting to continue her point. The clip became a viral sensation across Twitter, TikTok, and Instagram, evolving into a universal shorthand for a sudden realization, a slip of the tongue, or an unexpected mistake. It is widely celebrated as one of the most versatile reaction memes in internet culture, perfectly capturing the exact moment when someone needs to stop mid-sentence due to physical or social shock.