The High On Life meme originates from the 2022 comedic first-person shooter game developed by Squanch Games. Known for its distinct art style and fourth-wall-breaking humor, the game features sentient, talking weapons called Gatlians that possess hyper-expressive, often manic facial features. The 'High On Life' meme template typically captures characters with dilated pupils and wide, toothy grins, perfectly representing feelings of intense excitement, caffeine rushes, or genuine absurdity. It has become a staple for internet users wanting to convey a state of being overwhelmed by joy or chaotic energy in a way that is both surreal and relatable.