The 'Nobody Messes With Adam We' meme originates from the hit animated series Family Guy, specifically the Season 4 episode 'Sibling Rivalry' which aired in 2006. In this classic scene, the eccentric Mayor Adam West, voiced by the legendary real-life actor Adam West, is seen rearranging the gold letters of his name on his office sign. After removing the letters 'S' and 'T' from 'West,' he stares intently at the remaining letters and declares with bizarre conviction, 'Nobody messes with Adam We.' This clip is a staple of early 2000s surreal humor and has seen a resurgence as a versatile reaction video. It is commonly used to represent situations involving misplaced confidence, accidental typos, or moments where someone embraces a mistake as a new identity. It captures feelings of irrational aggression over something trivial and the humor of a character being their own worst enemy. Example captions include: 'When you make a typo in the group chat but decide to live with it,' 'Me after the barber ruins my hairline but I'm too shy to say anything,' and 'When you accidentally delete the wrong file and just accept your fate.'