This meme originates from the long-running animated sitcom 'Family Guy,' specifically the 2012 episode titled 'Forget-Me-Not.' In the scene, the character Peter Griffin, voiced by creator Seth MacFarlane, attempts to eat an apple as a healthy snack choice while his friends look on. His body immediately reacts with violent, jerky spasms as he shouts the iconic line, 'My body is rejecting it!' while dropping the fruit in agony. The clip has since become a viral reaction template used to represent a visceral or involuntary refusal of something 'good' or 'healthy' when someone is accustomed to chaos or bad habits. It is frequently applied to relatable scenarios like a student trying to study, a night owl seeing the morning sun, or a person trying to drink water instead of soda. These captions highlight the humor in how a person's internal system can feel poisoned by sudden bursts of productivity or self-improvement. Example caption ideas include: 'When I try to drink water instead of my 4th iced coffee,' 'Me trying to be productive for 5 minutes,' and 'My brain the second I open a textbook.'