The Deion Broxton's Bison Reaction meme stems from a viral video captured in March 2020 at Yellowstone National Park. Broxton, an NBC Montana reporter, was preparing for a segment when he spotted a herd of bison heading his way. His immediate reaction—uttering 'Oh my god, I ain't messing with you' while maintaining direct eye contact with the threat and promptly packing up his gear—resonated with millions. It quickly became the ultimate 'nope' meme, used to illustrate situations where a person wisely chooses to avoid a conflict, awkward circumstance, or impending disaster. Its popularity lies in Broxton's calm yet firm commitment to personal safety over professional duty, making it a relatable staple for anyone who knows when it is time to exit a bad situation.