The 'I Can't Do This Anymore' meme featuring TikTok superstar Charli D'Amelio originated from a candid video where she expressed a moment of emotional overwhelm and exhaustion. Fans quickly took the screenshot of her looking weary and turned it into a universal symbol for burnout, procrastination, and the drama of daily life. It is widely used on platforms like Twitter and TikTok to humorously exaggerate minor inconveniences, such as finishing a single chore or facing a long work week. The meme resonates because it captures the collective feeling of being 'done' with modern stressors, using one of the internet's most recognizable faces to ground the sentiment.