2B, the protagonist of the 2017 action RPG NieR: Automata, became an instant internet icon due to her striking design and the game's deep philosophical themes. While initially popular for her aesthetic appeal, she evolved into a versatile meme subject covering everything from existential dread to her frequent inclusion in dozens of crossover games like SoulCalibur and Final Fantasy XIV. The 2B meme often plays on the contrast between her stoic military nature and the chaotic situations fans place her in. Whether it's the iconic 'Glory to Mankind' catchphrase or jokes about her signature blindfold, 2B remains a staple of gaming culture and a go-to for memes about high-concept sci-fi and unexpected gaming cameos.