The Yotsuba Koiwai '404 Girl' meme features the energetic and innocent protagonist of the manga series Yotsuba&! by Kiyohiko Azuma. While the character is known for her everyday adventures, this specific imagery became an internet staple as the unofficial mascot for '404 Not Found' error pages, particularly on 4chan and other early imageboards. The meme typically depicts Yotsuba looking bewildered or shocked, perfectly capturing the frustration and confusion of landing on a broken link. Over the years, it has evolved into a versatile reaction image used to express cluelessness, missing information, or general site malfunctions across the web.