The 'What's New Pussycat?' meme primarily stems from comedian John Mulaney’s iconic stand-up bit about playing the eponymous Tom Jones song twenty-one times at a local diner to annoy the patrons. This story of psychological warfare via jukebox turned the 1965 classic into a symbol of hilarious, repetitive chaos. In the broader meme world, the phrase is often paired with images of confused or dapper cats, or used to herald a chaotic situation that is about to escalate. Whether you are referencing the Mulaney bit or just making a feline-themed joke, the template serves as the perfect vessel for unexpected repetition and lighthearted absurdity.