The 'Vault Boy Hold Up' meme features the iconic mascot of the Fallout video game franchise, Vault Boy, appearing confused or alarmed with a hand raised. While Vault Boy is known for his cheerful 'thumbs up' attitude, this edited version captures a moment of sudden realization or concern. It gained massive popularity on platforms like Reddit and Twitter as a reaction image used to respond to disturbing facts, dark humor, or situations that escalate far too quickly. The template perfectly encapsulates the feeling of needing to stop everything and ask for clarification when a conversation takes an unexpected turn.