The Vanya and Five meme originates from a scene in the second season of Netflix's The Umbrella Academy. It depicts Vanya Hargreeves and Number Five driving past each other in separate cars, both reacting with expressions of pure shock and confusion. First gaining massive popularity on platforms like Reddit in mid-2020, the template is widely used to illustrate awkward coincidences, unexpected encounters, or two different people realizing they are caught in the same chaotic situation. It has since become one of the most recognizable reaction formats from modern television.