The phrase 'If I can't smoke and cuss, I'm fucked' comes from the cult classic TV show Trailer Park Boys, which focuses on the misadventures of several residents of a fictional trailer park in Canada. The show is known for its irreverent humor, engaging characters, and a distinctive style that blends mockumentary with scripted comedy. The line captures the essence of a character's dependence on vices, which resonates with many fans who appreciate the blend of humor and realism in depicting struggles and desires in everyday life. In the context of the meme, it symbolizes a sense of frustration and helplessness when faced with restrictions on personal freedoms or comforts, striking a chord among viewers who relate to the sentiment.