The 'These Gays, They’re Trying To Murder Me' meme originates from the Season 2 finale of the HBO series The White Lotus. Delivered by the iconic Jennifer Coolidge as her character Tanya McQuoid, the line occurs during a moment of peak paranoia and frantic realization while she is trapped on a yacht. The scene instantly went viral due to Coolidge’s unique delivery and the campy absurdity of the situation. It has since become a staple of internet culture, used by fans to describe feelings of being overwhelmed, jokingly calling out minor inconveniences, or paying homage to one of the most memorable TV moments of the 2020s.