The Magic School Bus meme stems from the iconic 1994 educational animated series where Ms. Frizzle takes her class on scientifically impossible adventures. The most famous variation utilizes the show's intro sequence where Arnold wishes for a 'normal field trip,' only to be rebuffed by his classmates shouting, 'With the Frizz? No way!' This format became a viral sensation as a way to describe situations that are destined to be chaotic, unpredictable, or led by an eccentric personality. It is widely used to contrast a desire for stability with the reality of a wild situation, often appearing in fandoms, academic jokes, and workplace humor.