The 'That's Crazy, Man. Have You Ever Done DMT?' meme is a parody of comedian and podcaster Joe Rogan’s frequent redirection of intense or bizarre conversations toward the powerful psychedelic drug, N,N-Dimethyltryptamine. Originating from 'The Joe Rogan Experience,' the phrase highlights Rogan's well-known fascination with altered states of consciousness and his tendency to pivot from scientific or tragic topics into discussions about spiritual awakenings. It is widely used on social media to mock situations where someone gives a predictable or unrelated response to a complex story. The template serves as the ultimate punchline for any conversation that starts to get a little too 'out there' or needs a classic JRE-style interruption.