The 'Terrence Howard's Mayne' meme stems from the actor's distinct pronunciation of the word 'man,' most famously showcased in the 2005 film Hustle & Flow. Over the years, the internet transformed this quirk into a versatile reaction meme used to convey intensity, street wisdom, or faux-profound realizations. Recently, the meme saw a massive resurgence following Howard's viral interviews where he explained his unconventional theories on mathematics and physics, often referred to as 'Terryology.' Today, creators use the template to parody deep philosophical thoughts or to punctuate a statement with Howard's signature Southern drawl, making it a staple for both nostalgic movie fans and modern internet theorists.