The 'Squinting Woman' meme features Kalin Elisa, who posted a photo of herself in 2018 where she appeared to be out of breath and squinting at something in the distance. The image quickly went viral on Twitter as users identified with the struggle of trying to see something without glasses or reacting to confusing situations. It is primarily used to represent confusion, poor eyesight, or a skeptical reaction to something unbelievable. The meme's versatility has made it a staple for social media commentary on everything from reading tiny text to spotting a red flag from a mile away.