Spangles became an internet sensation in 2012 when photos of the cross-eyed rescue cat from South Carolina went viral on Facebook. Known for his distinctive strabismus and a vast wardrobe of costumes ranging from pirates to superheroes, Spangles captured the hearts of millions. The meme typically celebrates his 'derpy' yet lovable appearance, often used to represent confusion, innocence, or the joy of being unique. Spangles remains a beloved staple of cat culture, symbolizing how being different can be a source of global happiness.