Solitude in E Minor refers to a scene from the Season 1 SpongeBob SquarePants episode titled 'Culture Shock,' where Squidward Tentacles performs a somber, avant-garde clarinet piece at the Krusty Krab talent show. The phrase originally appears as a title card before Squidward’s performance, which is met with indifference and heckling from the audience. In internet culture, the meme is frequently used to depict feelings of isolation, being misunderstood, or the awkwardness of sharing something personal that others don't appreciate. It has since evolved into a versatile template for anything intentionally dramatic that results in a lonely or humorous outcome, often paired with the catchphrase 'Yeah, E minor, alright!'