The 'Sick Kaguya' meme originates from the popular anime 'Kaguya-sama: Love Is War,' specifically during a scene where the protagonist, Kaguya Shinomiya, collapses with a high fever. Her delirious and vacant expression resonated with fans, quickly becoming a symbol for being mentally exhausted, socially drained, or physically incapacitated. It is frequently used in internet culture to describe the 'brain-dead' state one enters after a long day of work, intense studying, or awkward social encounters. The template serves as a relatable visual shorthand for any situation where someone is functioning at zero percent capacity.